Publications TrialMatchAI: Advancing Precision Oncology with Open-Source Innovation We are proud to announce the publication of TrialMatchAI in Nature Communications (https://www.nature.com/articles/s41467-026-70509-w), a groundbreaking project developed as part of the EU EOSC4Cancer initiative. This work addresses a critical challenge in precision oncology: matching patients to relevant clinical trials using heterogeneous clinical data, including structured
Open Positions Stage M2 : AI-powered multimodal integration of spatial omics data Glioblastoma (GB) is an aggressive brain cancer, characterized by extensive infiltration and metabolic adaptations, yet not fully understood. Spatial transcriptomics (ST) and spatial metabolomics (and lipidomics) through Mass Spectrometry Imaging (MSI), are two powerful omics modalities that allow to dissect the tissue organisation of this cancer. Our bioinformatics team, led
A look back at the Open House Day of the IBGC (2025) Authors: Florian Specque, Daniel Garcia Ruano. On Saturday October 11th, in the context of the 2025 edition of the science festival ("FĂŞte de la science"), the IBGC opened its doors to the general public for an afternoon. It was the perfect occasion to discover the institute's
Open Positions Stage M2 : LLM-based prediction of metabolite-level drug responses in cancer cell lines from biomedical literature Stage M2 : LLM-based prediction of metabolite-level drug responses in cancer cell lines from biomedical literature
Seminars 14/03 Human and viral genomics of infections In this talk Vincent Pedergnana will present results from his research on hepatitis C virus and dengue virus using novel biostatistical approaches.
Seminars 29/11 Phyloformer: towards fast and accurate phylogeny estimation with self-attention networks Seminar by Laurent Jacob (CNRS Lyon) "Phyloformer: towards fast and accurate phylogeny estimation with self-attention networks"
Seminars 8/11 - Fridolin Gross: Predicting microRNA targets using a biochemical model combined with machine learning In this seminar Fridolin Gross will present his work on predicting microRNA targets using a biochemical model combined with machine learning
Machine Learning for antimicrobial resistance (AMR) prediction Ulysse Guyet will be giving a talk titled "ARSENAL: Antimicrobial ReSistance prEdictioN by mAchine Learning approach" at the ML Microbial Genomics workshop on Friday 23/09.
Seminars 31/05 - Kateryna Makova: Explaining and predicting disease occurrence from omics data In this seminar, Pr. Kateryna Makova from Penn State University will present her work on the prediction of disease occurrence from omics data at the Computational Biology and Bioinformatics Lab in Bordeaux
Projects Exploiting innate immunity of hepatocellular carcinoma to improve patients treatment Analysis of HCC tumour etiology based on multi-omic datasets including scRNAseq, spatial scRNAseq, bulk RNAseq and 16S microbiome sequencing
Projects Tumoral heterogeneity and multi-omics data integration Tumour heterogeneity analysis by deconvolution and multi-omic data integration to elucidate cancer phenotypes
Team À propos de l'équipe de bio-informatique et de biologie computationelle de Bordeaux Permettre la convergence entre "l'imagerie microscopique" et les "omiques" à travers la biologie computationelle
Seminars 12/04 - Samuel Chaffron (Tara Oceans) : Les Modèles De Réseau De Plancton Présentation de SAMUEL CHAFFRON au Computational Biology and Bioinformatics Lab de bordeaux sur la communauté microbienne dans l'océan mondial
Seminars 22/03 - Laurent Tichit (IMM) : Random Walk with Restart on Multilayer Biological Networks In this seminar, Dr. Laurent Tichit from Université D’aix-Marseille will present his work on random walk with restart on multilayer biological networks at Computational Biology and Bioinformatics Lab in Bordeaux
Seminars 01/03 - Emilien Peltier (ISVV) : Inheritance, Phenotypic Variation, And Missing Heritability Hidden Behind The Mitochondrial Genome
Seminars 18/01 - Clémence Frioux (PLEIADE) : Modélisation discrète du métabolisme, des organismes individuels aux écosystèmes microbiens In this seminar, Clémence FRIOUX from the INRIA research team PLEIADE will present her work on Discrete modeling of metabolism, from individual organisms to microbial ecosystems at the Computational Biology and Bioinformatics Lab in Bordeaux
Team New member: Slim Karkar Slim is the latest addition to the CB&B Team. How did you come to choose your area of research? > I came to work in bioinformatics because I wanted to apply my computer skills to biomedical and life science. The human genome project was an amazing scientific step
Publications DypFISH Dynamic Patterned FISH to Interrogate RNA and Protein Spatial and Temporal Subcellular Distribution > Anca F. Savulescu, Robyn Brackin, Emmanuel Bouilhol, Benjamin Dartigues, Jonathan H. Warrell, Mafalda R. Pimentel, Nicolas Beaume, Isabela C. Fortunato, Stephane Dallongeville, Mikaël Boulle, Hayssam Soueidan, Fabrice Agou, Jan Schmoranzer, Jean-Christophe Olivo-Marin, Claudio A. Franco, Edgar
Team About us Computational Biology and Bioinformatics is an interdisciplinary team at the CNRS institute in Bordeaux focused on multi-omics and imaging data integration. Our two main pillars are 1) Tackling real biological problems and 2) Combining different areas of technical expertise ...
